Warehouse Supply High Quality Chloroquine Diphosphate CAS 50-63-5 Chloroquine Diphosphate

• Customization: Available
• Powder: Yes
• Customized: Negotiable
• Model NO.: QS-Chloroquine Diphosphate
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Chloroquine Diphosphate
• Name: Chloroquine Diphosphate Powder
• Appearance: White Powder
• Colour: White
• Grade: Veterinary Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• CAS: 50-63-5
• Mf: C18h32cln3o8p2
• MW: 515.865
• Melting Point: 200 ° C
• Boiling Point: 460.6 ° C at 760 Mmhg
• Psa: 203.30000
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Chloroquine Diphosphate
• Origin: Xian
• Production Capacity: 1000kg/Month

Product Description

Warehouse Supply High Quality Chloroquine Diphosphate CAS 50-63-5 Chloroquine Diphosphate

Product Description

Product Details

Product Name	Chloroquine Diphosphate
Appearance	Chloroquine Diphosphate Powder
Assay	99%
MW	515.865
MF	C18H32ClN3O8P2

The main pharmacological effects of Chloroquine Diphosphate include anti malarial and anti amoebic effects. It belongs to the 4-aminoquinoline class of antimalarial drugs, which can inhibit the nucleic acid synthesis of malaria parasite schizonts, interfere with the growth and reproduction of malaria parasites, and have an efficient killing effect on the red phase schizonts of malaria parasites. Specifically, chloroquine phosphate can be used to treat chloroquine sensitive Plasmodium falciparum, Plasmodium vivax, and Plasmodium falciparum, and can be used for inhibitory prevention of malaria symptoms. In addition, it can also be used to treat extraintestinal amoebic disease, connective tissue disease, and photosensitive diseases (such as sunburn erythema).

Application&Function

Chloroquine Diphosphate is a multi-purpose drug, and its mechanism of action and indications are as follows:
1, Core drug action
Antimalarial effect
By inhibiting the nucleic acid synthesis of the red phase schizonts of malaria parasites and blocking their reproduction, it is effective against malignant malaria, intermittent malaria, and triple malaria.
Used for symptom control and preventive treatment of malaria.
Antiviral activity
In vitro experiments showed that it could inhibit 2019 novel coronavirus (EC50=1.13 μ M), interfere with the fusion of virus and host cell membrane and acidification of endosomes.
In 2020, the National Health Commission confirmed its potential therapeutic value for .
Anti amoebic effect
Used to treat extraintestinal amoebiasis (such as amoebic liver abscess).
Anti inflammatory and immune regulation
Treat connective tissue diseases such as rheumatoid arthritis and photosensitive diseases (such as sun induced erythema).
2, Mechanism of action
Nucleic acid synthesis inhibition: Inserting DNA double helix structure to prevent replication and RNA transcription.
Enzyme activity interference: Inhibits the heme polymerase of malaria parasites, leading to the accumulation of toxic heme.
Inhibition of viral endosome acidification: inhibits host cell autophagy and interferes with virus release.
3, Clinical application extension
Tumor research: Non specific inhibition of metalloproteinases (MMPs) and exploration of their anti-tumor potential.
Combined medication: It is used in combination with and other drugs to enhance the antiviral effect.
This drug plays an important role in malaria, viral diseases, and immune related diseases due to its broad-spectrum anti pathogen activity and multi-target mechanism.

 

Specification