Pharmaceutical Setipiprant Powder Androgenetic Setipiprant

• Customization: Available
• CAS No.: 866469-33-5
• Formula: C24h19fn2o3
• Model NO.: QS-Setipiprant
• EINECS: N/M
• Packaging Material: Metal
• Storage Method: Normal
• Shelf Life: >12 Months
• Nutrient Composition: Setipiprant
• Resource: Chemosynthesis
• The content of active substances: >99%
• Product Name: Setipiprant
• CAS Number: 866469-33-5
• Appearance: White Powder
• Mf: C24h19fn2o3
• MW: 234.29
• Melting Point: 225-230
• Density: 1.5/Cm3
• Assay: HPLC99%
• State: Powder
• TM: QS
• Size: 99%
• Name: Setipiprant Powder
• Made in: Xi′an
• Certification: GMP Hse ISO 9001 USP Bp
• Application: Pharmaceutical
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS
• Origin: Shaanxi Xi′an
• Production Capacity: 200kg/Month

Product Description

Pharmaceutical Setipiprant Powder Androgenetic Setipiprant
 

Product Description

Product Details

Product name	Setipiprant
Cas number	866469-33-5
Appearance	White powder
MF	C24H19FN2O3
MW	234.29

Streptopiram belongs to a class of drugs known as enzyme inhibitors, whose mechanism of action is to reduce cardiac load, dilate blood vessels, and improve the heart's pumping ability by inhibiting the activity of certain enzymes in the body. It mainly works by inhibiting the activity of angiotensin-converting enzyme (ACE). ACE is an enzyme that can convert angiotensin I to angiotensin II, and angiotensin II is a strong vasoactive substance that can constrict blood vessels and increase water and sodium retention. Therefore, inhibiting ACE activity can reduce cardiac load, expand blood vessels, and reduce water and sodium retention, thus improving the symptoms of cardiac insufficiency.
 

Application&Function

Pharmacological action
(1) Anti-inflammation and swelling effects: (1) The hyperpermeability of blood vessels was inhibited after oral administration of the drug in the heat-burned rat model of inflammation; (2) Oral administration can inhibit the inflammatory edema of rat skin caused by antiserum, and also inhibit the inflammatory edema caused by carrageenan, glucan, 5-hydroxytryptamine, bradykinin and other inflammatory substances in rats; (3) In vitro, it has a strong ability to decompose inflammatory polypeptide bradykinin; It has a strong solubility in fibrin and fibrin, but has almost no effect on albumin, α- and β-globulin and other body proteins. (2) Promote the dissolution and excretion of sputum and concentrated liquid: reduce the weight and viscosity of dry matter in nasal mucus in patients with chronic paranasal sinusitis; In rabbits with subacute bronchitis due to exposure to sulfur dioxide gas, the sputum viscosity decreased significantly. (3) Promoting the migration of antibiotics to the focal site: promoting ampicillin migration to the maxillary sinus in patients with chronic paranasal sinusitis; In rabbits with experimental cystitis, it can promote the migration of methicillin to the bladder wall.

pharmacokinetics
Sereptidase can be absorbed from the intestine when taken orally, but in small amounts. After oral administration, it can be widely distributed in lymph, bronchus, lungs, bladder, blood and other tissues and body fluids, among which the concentration in lymph tissue is high, and the concentration in tissue and blood is generally positively correlated with flow. When adults take serrepeptide 5mg, the peak time of blood and lymphoid tissue is about 1h, and the maintenance time is about 4 ~ 5h. The drug concentration in lymphoid tissue is longer than that in blood. Serrepeptide is metabolized in the body, and the main metabolites and part of the original drug are excreted in feces and urine.

Specification