Antibiotic Drug CAS 1403-66-3 Gentamicin Veterinary Drug Gentamicin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: QS-Gentamicin
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Gentamicin
• Name: Gentamicin Powder
• Appearance: White Powder
• Colour: White
• Grade: Pharmaceutical Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• Mf: C60h123n15o21
• MW: 1390.71
• CAS: 1403-66-3
• Density: 1.3
• Melting Point: 102-108c
• Boiling Point: 760 Mmhg
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Gentamicin
• Origin: Xian
• Production Capacity: 10000kg/Month

Product Description

Antibiotic Drug CAS 1403-66-3 Gentamicin Veterinary Drug Gentamicin

Product Description

Product Details

Product Name	Gentamicin
Appearance	White Powder
Assay	99%
MW	1390.71
MF	C60H123N15O21

CAS 1403-66-3 gentamicin is a type of antibiotic called gentamicin.
Gentamicin belongs to the broad-spectrum aminoglycoside antibiotics, which not only have antibacterial effects on Gram negative bacteria, but also have antibacterial effects on positive cocci. At the same time, it also has sustained antibacterial effects at low concentrations, which means that after removing the drug or when the drug concentration is lower than the antibacterial concentration, it can still continue to inhibit bacterial growth for a certain period of time.

Application&Function

Gentamicin is an aminoglycoside antibiotic that primarily exerts its antibacterial effect by inhibiting bacterial protein synthesis.
The specific mechanism of action is as follows:
Gentamicin can first passively diffuse through the extracellular membrane porin, and then enter the cell through the transport system and irreversibly bind to the separated ribosomal 30s subunit, leading to the destruction of the A-site.
In addition, Gentamicin can also prevent the correct localization of aminoacyl tRNA at position A, especially hindering the binding of methionine tRNA, thereby interfering with the assembly of functional ribosomes and inhibiting the formation of the 70s initiation complex.
Gentamicin can also induce incorrect matching of tRNA and mRNA code triplets, causing the complete ribosome's 30s subunit to misread the genetic code, resulting in incorrect amino acid insertions into protein structures and abnormal, non functional protein synthesis.
Gentamicin can also hinder the binding of termination factors to the A-site, preventing the release of synthesized peptide chains and preventing the complete dissociation of ribosomes at 70 seconds.
Gentamicin can also hinder the process of ribosome disassembly and assembly, leading to ribosome depletion in bacteria.

Specification