Customization: | Available |
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Powder: | Yes |
Customized: | Negotiable |
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Product Name | Fasudil Hydrochloride |
Apperance | White to off-white powder |
CAS | 105628-07-7 |
MF | C14H17N3O2S·HCl |
MW | 327.83 g/mol |
Fasudil Hydrochloride specifically inhibits Rho kinase (ROCK), regulates myosin light chain phosphorylation, thereby relaxing vascular smooth muscle and improving blood flow. Its clinical applications include relieving cerebral vasospasm after subarachnoid hemorrhage, and demonstrating anti-inflammatory, anti fibrotic, and neuroprotective potential. In recent years, research has found that it has therapeutic effects in disease models such as pulmonary hypertension, glaucoma, and Alzheimer's disease. In addition, due to its ability to penetrate the blood-brain barrier, Fasudil has attracted much attention in the research of central nervous system diseases and is a key tool compound for the study of the ROCK signaling pathway.