Stock Material Paracetamol Acetaminophen Paracetamol

• Customization: Available
• CAS No.: 103-90-2
• Formula: C8h9no2
• Model NO.: QS-Paracetamol
• EINECS: 203-157-5
• Packaging Material: Negotiable
• Storage Method: Normal
• Shelf Life: 2year
• Nutrient Composition: Paracetamol
• Resource: Paracetamol
• The content of active substances: 99%
• Product Name: Paracetamol
• Name: Paracetamol Powder
• Assay: HPLC 99%
• CAS: 103-90-2
• Appearance: White Powder
• Color: White
• Mf: C8h9no2
• MW: 151.16
• Melting Point: 168-172ºC
• Boiling Point: 273.17c
• Density: 1.293
• Test Method: HPLC
• Grade: Pharmaceutical Grade
• Application: Antipyretic
• Specific: COA
• Transport Package: Negotiable
• Specification: 99%
• Trademark: QS
• Origin: Shaanxi Xi′an
• Production Capacity: 5000kg/Month

Product Description

Stock Material Paracetamol Acetaminophen Paracetamol

Product Description

Product Detials

Product Name	Paracetamol
Apperance	White to off-white crystalline powder
CAS	103-90-2
MF	C8H9NO2
MW	151.16 g

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Acetaminophen (also known as paracetamol) is a widely used non-opioid analgesic and antipyretic medication, classified as an aniline derivative. Its chemical name is N-acetyl-para-aminophenol (APAP).It appears as a white, odorless, crystalline powder with a slightly bitter taste and is soluble in water (1:70) and more soluble in alcohol (1:7).

Application&Function

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 1.Clinical Applications
Pain Management:
Headaches, dental pain, musculoskeletal pain: Comparable efficacy to NSAIDs for mild pain.
Post-surgical pain: Often combined with opioids (e.g., after dental procedures).
Fever Reduction:
First-line for pediatric fever (preferred over aspirin due to Reye's syndrome risk).
Chronic Conditions:
Osteoarthritis: Used when NSAIDs are contraindicated (e.g., in CKD patients).
2. Pharmacokinetics
Absorption: Rapid oral absorption (peak plasma levels in 30–60 mins).
Metabolism:
90% liver metabolism via glucuronidation/sulfation (non-toxic pathways).
5–10% oxidized by CYP2E1 to N-acetyl-p-benzoquinone imine (NAPQI), a hepatotoxic metabolite detoxified by glutathione.
Excretion: Renal (half-life: 1–4 hours).
3. Advantages Over NSAIDs
GI Safety: No gastric irritation or ulcer risk.
No Antiplatelet Effects: Safe for pre-surgical use.
Pediatric Use: Preferred for fever in children.

Specification

Certificate of Analysis