| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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| Product Name | Dabrafenib |
| CAS | 1195765-45-7 |
| Appearance | White crystalline powder |
| MF | C23H20F3N5O2S2 |
| MW | 519.561 |
Pharmacological action
Dabrafenib is a targeted anticancer drug that inhibits the growth and spread of tumors by blocking signaling pathway activation in cancer cells by inhibiting the activity of BRAF V600E or V600K mutant proteins. This mechanism enabled Dabrafenib to perform well in clinical trials, significantly extending progression-free survival and overall survival in patients .
Side effect
Dabrafenib use may cause a range of side effects, common ones include:
skin lesions : such as rash, pruritus, erythema .
Systemic symptoms : fever, fatigue, joint pain, headache, nausea, vomiting, diarrhea, and hyperglycemia .
other serious side effects such as eye problems, heart problems and abnormal liver function can also occur .
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