Good Quality CAS 58-93-5 Hydrochlorothiazide Purity Hydrochlorothiazide

• Customization: Available
• CAS No.: 58-93-5
• Formula: C7h8cln3o4s2
• Model NO.: QS-Hydrochlorothiazide
• EINECS: 200-403-3
• Packaging Material: Negotiable
• Storage Method: Normal
• Shelf Life: >12 Months
• Nutrient Composition: Hydrochlorothiazide
• Resource: Hydrochlorothiazide
• The content of active substances: >99%
• Product Name: Hydrochlorothiazide
• Name: Hydrochlorothiazide Powder
• Appearance: White Powder
• Colour: White
• Grade: Pharmaceutical Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• Density: 1.693
• Mf: C7h8cln3o4s2
• MW: 297.73912
• Melting Point: 273-275c
• Boiling Point: 577c
• Accurate Mass: 296.9644758
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Hydrochlorothiazide
• Origin: Xian
• Production Capacity: 1000kg/Month

Product Description

Good Quality CAS 58-93-5 Hydrochlorothiazide Purity Hydrochlorothiazide

Product Description

Product Details

Product Name	Hydrochlorothiazide
Appearance	Hydrochlorothiazide Powder
Assay	>99%
MW	297.73912
MF	C7H8ClN3O4S2
Melting point	273-275C
Boiling point	577C

Hydrochlorothiazide has a moderate diuretic effect. By acting on the cortical part of the ascending branch of the medullary loop, the active reabsorption of Cl - and passive absorption of Na+in this area are inhibited, thereby promoting diuresis. In addition, this product also has antihypertensive and antidiuretic effects. Suitable for various types of edema, especially cardiogenic edema. It can also be used as a antihypertensive medication for the treatment of mild to moderate hypertension.

Application&Function

Hydrochlorothiazide is a thiazide intermediate acting diuretic mainly used to treat edema and other related diseases.
The following are the main pharmacological effects of Hydrochlorothiazide:
1. Diuretic effect: Hydrochlorothiazide acts as a diuretic by inhibiting the reabsorption of sodium chloride by the kidneys, increasing the amount of urine excreted. This helps reduce excess water in the body and alleviate symptoms of edema.
2. Hypotensive effect: This drug can open calcium activated potassium (KCA) channels, producing a direct vasodilation effect, thereby lowering blood pressure.
3. Reduce fibrosis: Hydrochlorothiazide can improve heart function and reduce fibrosis, which is helpful for treating diseases such as hypertension and heart disease.
4. Anti TGF - β/Smad signaling pathway: This drug can also inhibit the transforming - β (TGF - β)/Smad signaling pathway, which may be related to its anti fibrotic effect.

Specification