Veterinary Grade API Trimethoprim Powdre Raw Material Trimethoprim

• Customization: Available
• Powder: Yes
• Customized: Negotiable
• Model NO.: QS-Trimethoprim
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Trimethoprim
• Name: Trimethoprim Powder
• Appearance: White Powder
• Colour: White
• Grade: Veterinary Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• CAS: 738-70-5
• Mf: C14h18n4o3
• MW: 290.323
• Density: 1.252
• Melting Point: 199-203c
• Boiling Point: 526c at 760 Mmhg
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Trimethoprim
• Origin: Xian
• Production Capacity: 1000kg/Month

Product Description

Veterinary Grade API Trimethoprim Powdre Raw Material Trimethoprim

Product Description

Product Details

Product Name	Trimethoprim
Appearance	Trimethoprim Powder
Assay	>99%
MW	290.323
MF	C14H18N4O3
Melting point	199-203C
Boiling point	526C at 760 mmHg

Trimethoprim is a dihydrofolate reductase inhibitor that exerts antibacterial effects by selectively inhibiting bacterial folate metabolism (with an affinity for DHFR 10000 times higher than that of mammals). It is effective against most Gram positive bacteria (such as Staphylococcus aureus) and negative bacteria (such as Escherichia coli and Salmonella). Clinically, it is mainly used to treat urinary tract infections, respiratory tract infections, and acute exacerbation of chronic bronchitis. It is often combined with sulfamethoxazole to form a compound of Co trimoxazole to enhance antibacterial efficacy and reduce drug resistance. It is also used in the veterinary field to prevent and treat digestive and respiratory infections in livestock and poultry. Attention should be paid to the possibility of folate deficiency (manifested as megaloblastic anemia), and it is recommended to store in the dark at 2-8 ° C. It was listed as an important antibacterial drug by WHO in 2017.

Application&Function

Pharmacological effects and uses of Trimethoprim

Antibacterial mechanism
By selectively inhibiting bacterial dihydrofolate reductase (DHFR), blocking folate metabolism, and interfering with DNA synthesis, it is effective against both Gram positive bacteria (such as Staphylococcus aureus) and negative bacteria (such as Escherichia coli).

Clinical application
Used alone: for treating urinary tract infections, respiratory tract infections, and intestinal infections.
Combination sulfonamide drugs (such as compound sulfamethoxazole): synergistically enhance antibacterial effects, used for pneumonia, Shigella disease, etc.
Animal use: prevention and treatment of poultry colibacillosis, coccidiosis, etc.

Specification