| Customization: | Available |
|---|---|
| Certification: | RoHS, BRC, ISO, FDA, HACCP |
| Storage Method: | Normal |
|
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Product name | Luteolin |
| Assay | 98% |
| Appearance | Yellow Needle Powder |
| MF | C15H10O6 |
| MW | 286.23 |
Luteolin, mostly in the form of glycoside exists in a variety of plants, these plants in the whole leaf of green orchid, pepper, wild chrysanthemum, honeysuckle, Perilla content is higher. It has antitussive and expectorant effects. According to the latest research, respiratory symptoms cough, sputum, wheezing, are related to chronic airway inflammation. For example, cough, sputum and wheezing caused by bronchial asthma, chronic obstructive pulmonary disease, chronic pharyngitis and allergic rhinitis are all believed to be related to local inflammatory infiltration. The existence of inflammation makes the immune response of the airway confused, and patients often have increased airway reactivity. Treatment should first eliminate the chronic inflammatory infiltration of the airway. Glucocorticoids are commonly used to eliminate airway inflammation. However, glucocorticoid has many side effects and is not suitable for long-term use. Studies have shown that luteolin inhibits macrophage phosphorylation, inhibits the activity of transcription factor NF-kB, and can inhibit the production of cytokines IL-6 and TNF-a by macrophages induced by lipopolysaccharide (LPS). In addition, studies have also shown that luteolin can inhibit uric acid production and promote uric acid excretion. The latter two cytokines play a very important role in the mechanism of inflammation and are sensitive indicators reflecting the degree of inflammation. Luteolin can also increase IFN-γ, decrease specific Ig-E, and reduce eosinophilic infiltration. In addition to anti-inflammatory and anti-allergic effects, luteolin also has anti-PDE, anti-SARS, and HIV properties, because it inhibits the activity of SARS virus pre-S protein, thereby preventing its entry into host cells. It is used to treat chronic cough caused by COPD, bronchial asthma, chronic pharyngitis, allergic rhinitis, etc.
){kind=link}