Bulk CAS 36791-04-5 Ribavirin 99% Purity Ribavirin Pharmaceutical Ribavirin

• Customization: Available
• CAS No.: 36791-04-5
• Formula: C8h12n4o5
• Model NO.: QS-Ribavirin
• EINECS: 636-825-3
• Packaging Material: Negotiable
• Storage Method: Normal
• Shelf Life: 2 Years
• Nutrient Composition: Ribavirin
• Resource: Ribavirin
• The content of active substances: 99%
• Density: 2.08 g/cm3
• Melting Point: 174-176°c
• Boiling Point: 639.8ºC at 760 Mmhg
• Refractive Index: -36 ° (C=1, H2O)
• Flash Point: 340.7ºC
• Vp: 5.1X10-13 mm Hg at 25 Deg C (Est)
• Psa: 143.72000
• Logp: -2.31120
• Solubility: >=10 G/100 Ml at 19 Oc
• appearance: White Powder
• Storage: Store in a Sealed Container Away From Light
• Pka: 12.95±0.70(Predicted)
• Spectral Characteristic: Specific Optical Rotation: -36.5 Deg at 25 Deg C/D
• Hazard Category Code: R61
• Wgk Germany: 3
• Transport Package: Negotiable
• Specification: 99%
• Trademark: QS
• Origin: Xi′an Shaaxi
• Production Capacity: 500kg/Month

Product Description

Bulk CAS 36791-04-5 Ribavirin 99% Purity Ribavirin Pharmaceutical Ribavirin

Product Description

Product Detials

Product Name	Ribavirin
Apperance	White powder
CAS	36791-04-5
MW	C8H12N4O5
MW	244.20500

Ribavirin, also known as ribavirin, triazolazole nucleoside, nico, etc., is a broad-spectrum and potent antiviral drug and is currently widely used in the prevention and treatment of viral diseases. Common dosage forms include injections, tablets, oral liquids, aerosols, etc. Ribavirin has few side effects and a low incidence of adverse reactions. According to its pharmacological effects, it should be noted that long-term use of large doses of this drug may cause leukopenia, anemia, and elevated serum transaminase and bilirubin. Blind and excessive medication should be avoided.

Application&Function

Manufacturing method
Using nucleosides or nucleotides as raw materials, guanosine and guanosinic acid are first hydrolyzed under the action of glacial acetic acid and acetic anhydride to generate ribose-1-phosphoric acid. Then, under the catalysis of di-p-nitrophenol, it reacts with triazide acetamide to form a condensate, which is obtained through amolysis. Guanosine (or guanosine monophosphate) [acetic anhydride, glacial acetic acid]→[Hydrolysis] ribose-1-phosphate [bis -(p-nitrophenol) -phosphate ester]→[triazide carboxylamide] condensate [amolysis]→ triazole nucleosidase synthesis method First hydrolyzes guanosine and guanosine monophosphate under the action of pyrimidine nucleoside phosphorylase to generate ribose-1-phosphate Then, under the action of purine nucleoside phosphorylase, it reacts directly with triazolide to form triazole nucleoside. Guanyside (or guanylate acid) [pyrimidine nucleoside phosphorylase]→ ribose-1 - nucleic acid [purine nucleotiladase]→ triazole nucleoside.

Purpose
Ribavirin (ICN-1229) is a broad-spectrum antiviral agent that can inhibit viruses such as HCV, HIV, and RSV. Ribavirin also has activity against orthopoxvirus and smallpox virus.

Specification

Certificate of Analysis