Purity Medetomidine HCl Powder Medetomidine

• Customization: Available
• CAS No.: 86347-15-1
• Formula: C13h17cln2
• Model NO.: QS-Medetomidine
• EINECS: 2017-001-1
• Packaging Material: Negotiable
• Storage Method: Normal
• Shelf Life: >12 Months
• Nutrient Composition: Medetomidine
• Resource: Medetomidine
• The content of active substances: >99%
• Product Name: Medetomidine
• Name: Medetomidine Powder
• Appearance: White Powder
• Colour: White
• Grade: Pharmaceutical Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• Density: N/a
• Melting Point: 166c
• Boiling Point: 381.9c
• Accurate Mass: 236.1080262
• Mf: C13h17cln2
• MW: 236.743
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Medetomidine
• Origin: Xian
• Production Capacity: 500kg/Month

Product Description

Purity Medetomidine Hcl Powder Medetomidine

Product Description

Product Details

Product Name	Medetomidine
Appearance	Medetomidine Powder
Assay	>99%
MW	236.743
MF	C13H17ClN2
Melting point	166C
Boiling point	381.9C

Medetomidine is a chemical substance with the chemical name ®- 4- [1- (2,3-dimethylphenyl) ethyl] -1H imidazole hydrochloride, commonly known as metoclopramide hydrochloride.
Metformin hydrochloride is an orally active α 2-adrenoceptor agonist with a Ki value of 1.08 nM. It has sedative and analgesic effects, and can induce peripheral vasoconstriction by activating α 2-adrenergic receptors on blood vessels. In anesthetized rats, medetomidine (1-100 micrograms/kg, intravenous injection) caused a dose-dependent transient decrease in blood pressure and heart rate. In rats with brain and spinal cord destruction, medetomidine showed effective vasopressor effects (PD501.7 μ g/kg) and sympathetic inhibition effects (ID501.6 μ g/kg) without affecting basal heart rate. Medetomidine induces dose-dependent sedative effects, causing loss of positive reflex and lowering body temperature at high doses (100 micrograms/kg). Medetomidine causes a decrease in the turnover rate of biogenic amines in the brain, dose-dependent inhibition of norepinephrine (NE) turnover, and inhibition of dopamine turnover in the brain at high doses, reducing serotonin turnover. Medetomidine HCl is a selective α 2-adrenoceptor agonist with a Ki of 1.08 nM, which is 1620 times more selective than acting on α 1-adrenoceptor.

Application&Function

Medetomidine is an orally active alpha 2 adrenergic receptor agonist, whose pharmacological effects include sedation, analgesia, and constriction of peripheral blood vessels.
Pharmacological action
1. Sedative effect: In anesthetized rats, metoclopramide causes a dose-dependent transient decrease in blood pressure and heart rate. In rats with brain and spinal cord destruction, metoclopramide showed effective vasopressor and sympathetic inhibition effects without affecting basal heart rate. Metformin causes dose-dependent sedative effects, leading to loss of positive reflexes and a decrease in body temperature at high doses.
2. Analgesic effect: Metformin can induce peripheral vasoconstriction by activating α 2-adrenergic receptors on blood vessels.

Specification