Best Price Halofuginone Hydrobromide Animal Drug Halofuginone Hydrobromide
Product Description
Product Details
| Product name |
Halofuginone Hydrobromide |
| Assay |
99% |
| Appearance |
White to off - powder |
| MF |
C16H17BrClN3O3.HBr |
| MW |
495.59 |
Halofvone hydrobromide is a chemical with the formula C16H18Br2ClN3O3 that is used as an anticocciditic agent in feed additives and to treat Taylor's pyrococcidiosis.
Application&Function
Halofuginone hydrobromide is a competitive inhibitor of prolyl-tRNA synthetase with a Ki of 18.3 nM. It has a variety of pharmacological effects, including:
Inhibits type I collagen synthesis :
Halofuginone hydrobromide is a specific inhibitor of type I collagen synthesis, alleviating osteoarthritis by inhibiting TGF-β activity.
pulmonary vasodilation :
It is an effective pulmonary vasodilator capable of activating Kv channels and blocking voltage-gated, receptor-operated and storage-operated Ca² + channels .
Anti-inflammatory, anti-malaria, anticancer, and anti-fibrotic properties : Halofuginone hydrobromide also has anti-inflammatory, anti-malaria, anticancer, and anti-fibrotic properties .
In addition, Halofuginone hydrobromide's physicochemical properties include: melting point 247°C (decomposition), molecular formula C16H18Br2ClN3O3, molecular weight 495.59300, insoluble in water, methanol, and dimethyl sulfoxide
Specification
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