99% Purity Pioglitazone HCl Pioglitazone

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: QS-Pioglitazone
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Pioglitazone
• Name: Pioglitazone Powder
• Appearance: White Powder
• Colour: White
• Grade: Pharmaceutical Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• Mf: C19h20n2o3s
• MW: 356.4387
• CAS: 105355-27-9
• Density: 1.26
• Melting Point: 183-184c
• Boiling Point: 760 Mmhg
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Pioglitazone
• Origin: Xian
• Production Capacity: 10000kg/Month

Product Description

99% Purity Pioglitazone Hcl Pioglitazon

Product Description

Product Details

Product Name	Pioglitazone
Appearance	White Powder
Assay	99%
MW	356.4387
MF	C19H20N2O3S

Pioglitazone is an anti diabetes drug, mainly used to treat type 2 diabetes (non dependent diabetes, NIDDM).
Pioglitazone is a thiazolidinedione anti diabetes drug, which is an sensitizer. Its mechanism of action is related to the presence of , which can reduce resistance in peripheral tissues and liver, increase dependent glucose processing, and reduce hepatic glucose output. Pioglitazone selectively activates the peroxisome activated receptor - γ (PPAR - γ), which regulates the transcription of many related genes that control glucose and lipid metabolism. The metabolic changes caused by this drug lead to an increase in tissue response dependent on . Due to the increased effect of pioglitazone on circulating (i.e. reducing resistance), it cannot lower blood glucose levels lacking endogenous .

Application&Function

Pioglitazone is a drug used to treat type 2 diabetes, belonging to thiazolidinediones (TZDs). The following is detailed information about the pharmacological effects of pioglitazone:
Pharmacological action
Pioglitazone is an sensitizer that primarily reduces blood glucose levels by increasing the sensitivity of peripheral tissues to . The specific mechanism of action includes:
Increase sensitivity: By activating receptor gamma (PPAR - γ), the sensitivity of adipose tissue and muscle tissue to is increased, and the utilization rate of is improved, thereby reducing blood sugar.
Inhibit hepatic glycogen breakdown and gluconeogenesis: reduce hepatic glucose output, further lowering blood glucose levels.

Specification