Pharmaceutical Intermediate Hydroxylamine Hydrochloride Purity Hydroxylamine Hydrochloride Powder
Product Details
| Product Name |
Hydroxylamine Hydrochloride |
| Apperance |
White Powder |
| CAS |
5470-11-1 |
| MF |
Clh4no |
| MW |
69.488 |
Production method
The sodium nitrite synthesis method (oxime method) involves adding water to the reactor, stirring, and then adding sodium nitrite in several portions, followed by acidification with sulfuric acid. The acidified material is sent into the hydrolysis reactor, acetone is added, and then neutralized with liquid alkali. The neutralized liquid is distilled to obtain acetone oxime. Acetone oxime and hydrochloric acid are added to the salt formation reactor to react, generating hydroxylamine hydrochloride and acetone. Acetone is recycled and reused; Hydroxylamine hydrochloride is concentrated, cooled and crystallized, separated by centrifugation and dried to obtain the finished product. Raw material consumption quota: Sodium nitrite (95%) 1,770 kg/t, sodium metabisulfite (64% SO2) 5,418 kg/t, acetone (98%) 1,175 kg/t. 2. Nitromethane method: Nitromethane reacts with hydrochloric acid and water to produce hydroxylamine hydrochloride. According to HGB3044-76, the hydroxylamine hydrochloride product is a white crystal. The content of the second-grade product is ≥98.5, and that of the third-grade product is ≥97%. Raw material consumption quota: Nitromethane 1200kg/t, hydrochloric acid (30%) 1500kg/t.
Application&Function
Purpose
It is mainly used as a reducing agent and an imaging agent. In organic synthesis, it is used to prepare oxime, and also serves as a raw material for the synthesis of anti-cancer drugs (hydroxyurea), sulfonamide drugs (sulfamethoxazole), and pesticides (methomyl). It is used as a depolarizing agent in electroanalysis, as a short-term non-coloring stop agent in the synthetic rubber industry, and for the determination of acetal degree, etc.
Used as a reducing agent and imaging agent; Used for the preparation of oxime in organic synthesis; Used as a depolarizer in electrical analysis; Inorganic analytical reducing agent Fatty acids and antioxidants in soap; Analyze formaldehyde, camphor and glucose, etc. Organic analysis tests for aldehydes and ketones; Microanalysis of sulfonic acid Determination of magnesium content in steel.
Specification
Audited Supplier 
){kind=link}