Pharmaceutical Raw Materia Sulfaguanidine Powder Sulfaguanidine
Product Description
Product Details
| Product Name |
Sulfaguanidine |
| Appearance |
Sulfaguanidine Powder |
| Assay |
>99% |
| MW |
214.2449 |
| MF |
C7H10N4O2S |
| Melting Point |
193C |
| Boiling point |
488.4C |
Sulfaguanidine is a sulfonamide drug mainly used to treat bacterial dysentery and enteritis, and can also be used to prevent infections after intestinal surgery.
Sulfonamide drugs are competitive inhibitors of bacteria against aminobenzoic acid. Sulfonamide guanidine is an inhibitor of dihydrofolate reductase (DHFR). Sulfonamide drugs have activity against both Gram positive and Gram negative bacteria. The resistance mode is achieved through alternative pathways such as changes in dihydrofolate synthase or folate synthesis.
Application&Function
Sulfonamide is an effective antibiotic mainly used to treat various bacterial dysentery and enteritis. Its mechanism of action is to inhibit the synthesis of nutritional factors by intestinal bacteria, hindering the growth of Gram negative Escherichia coli. In addition, it can also be used to prevent bacterial infections before intestinal surgery.
The main function of sulfamethoxazole in biochemical research is to prevent the synthesis of folate, and it can be used to study its effects on microspore growth and host cell viability.
Sulfonamide guanidine is a sulfonamide antibiotic whose biochemical/physiological function is to inhibit dihydrofolate synthesis by suppressing dihydropteroate synthase. Sulfonamide, as a competitive inhibitor of aminobenzoic acid (PABA; essential for folate synthesis in bacteria), and sulfamethoxazole, as an inhibitor of dihydrofolate reductase, have activity against both Gram positive and Gram negative bacteria. This resistance mode is achieved through changes in dihydropteroate synthase or alternative pathways of folate synthesis.
In biochemical research, sulfamethoxazole is used as an important research tool because it can prevent the synthesis of folate, thereby affecting the growth and metabolism of microorganisms. By studying the effects of sulfamethoxazole on microsporide growth and host cell viability, scientists can better understand the growth mechanism, metabolic pathways, and drug microbe interactions of microorganisms, which is of great significance for the development of new antibacterial drugs and treatment strategies. In addition, sulfamethoxazole is also used in the pharmaceutical industry, generally as an important raw material for sulfamethoxazole drugs such as SM2 and SD, indicating its application value and potential in the modern pharmaceutical field.
Specification
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