Pharma CAS 1622902-68-4 Abrocitinib Powder Abrocitinib

• Customization: Available
• CAS No.: 1622902-68-4
• Formula: C14h21n5o2s
• Model NO.: QS-Abrocitinib
• EINECS: N-M
• Packaging Material: Negotiable
• Storage Method: Normal
• Shelf Life: >12 Months
• Nutrient Composition: Abrocitinib
• Resource: Abrocitinib
• The content of active substances: >99%
• Product Name: Abrocitinib
• Name: PF-04965842(Abrocitinib)
• Appearance: White Powder
• Colour: White
• Pka: 10.55±0.40
• Grade: Pharmaceutical Grader
• Assay: >99%
• Application: Pharmaceutica
• Specific: COA
• Test Method: HPLC
• Complexity: 474
• Mf: C14h21n5o2s
• MW: 323.42
• Density: 1.36
• Psa: 99.4
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Abrocitinib
• Origin: Xi`an
• Production Capacity: 10kg/Month

Product Description

Pharma CAS 1622902-68-4 Abrocitinib Powder Abrocitinib
 

Product Description

Product Details

Product name	Abrocitinib
Cas number	1622902-68-4
Appearance	White powder
MF	C14H21N5O2S
MW	323.42

Abrocitinib (PF-04965842, PF04965842), Also known as Abrotinib, it is an orally administered JAK1 selective inhibitor with an IC50 of 29 nM, which can be used for autoimmune diseases. The overexpression and mutation of JAK1 are closely related to the occurrence and development of tumors. The IC50 values of Abrotinib on JAK2/3 and TYK2 were 803 nM and> 10 μ M and 1.253 μ M.

Application&Function

PF-04965842 (Abrotinib) has achieved positive results in multiple phase 3 clinical trials targeting patients with moderate to severe atopic dermatitis. It has shown statistically significant improvements in skin symptom clearance rate and disease severity, and rapidly improves itching symptoms in patients compared to placebo.

Specification