| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product name | Florfenicol |
| Cas number | 73231-34-2 |
| Apperance | White Powder |
| MF | C12H14Cl2FNO4S |
| MW | 358.213 |
Oral administration has a good protective effect against Pasteurella infection in yellow tailed fish, Edwardsiella tarda infection in eels, Vibrio parahaemolyticus infection in goldfish and eels, and Vibrio parahaemolyticus infection in salmon, with efficacy exceeding other commonly used antibiotics. Flufenicol has a significant therapeutic effect on bovine respiratory diseases. Hass et al. reported that the cure rate (80%) of Flufenicol treated bovine respiratory diseases by intramuscular injection at a dose of 20mg/kg was significantly higher than that of amoxicillin treatment group (50%). Madelent et al. reported that with the same dose of treatment for respiratory diseases, the cure rate of florfenicol (91%) was significantly higher than that of streptomycin (41%). Ueda treated artificially induced porcine actinobacillus pleuropneumonia with 50ppm mixed feeding, with a cure rate of 100%; The cure rate of the streptomycin treatment group (200ppm) was less than 50%. Craene reported that a single dose intravenous injection of fluofenicol (20mg/kg) in cattle can penetrate well into cerebrospinal fluid and can be used as the preferred drug for treating meningitis. Pharmacokinetic studies of florfenicol in lactating cows have shown that breast perfusion administration has better absorption than intramuscular injection, and the plasma concentration is significantly higher than that after intravenous injection for 4 hours. The bioavailability (54%) is higher than that of intramuscular injection (38%), which is of great practical significance for breast perfusion administration in the treatment of bovine mammary glands. After oral administration of florfenicol (30mg/kg) to broiler chickens, the bioavailability was 55.3% and the plasma protein binding rate was 18.5%. After injection of florfenicol (30mg/kg) to broiler chickens, the bioavailability was 96.6%; After intramuscular injection of florfenicol (30mg/kg) into ducks infected with Bacillus subtilis, the bioavailability was 73%, higher than that of healthy ducks
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