Factory Supply Chrysin Extract Chrysin Powder Purity Chrysin
Product Description
Product Details
| Product Name |
Chrysin |
| Apperance |
yellow powder |
| CAS |
480-40-0 |
| MF |
C15H10O4 |
| MW |
254.241 |
Chrysin is mainly found in passion fruit, honey and propolis. It is a potential therapeutic and preventive agent that can inhibit the proliferation and invasion of various human cancer cells. Although Chrysin has anti-cancer effects in various cancers, little is known about its functional role in ovarian cancer, which has a poor prognosis and is chemotherapy-resistant to traditional treatment drugs. Chrysin inhibits the proliferation of ovarian cancer cells and induces cell death by increasing reactive oxygen species (ROS) production and cytoplasmic Ca2+ levels, as well as inducing mitochondrial membrane potential (MMP) loss. In the concentration response experiment, Chrysin activated the MAPK and PI3K/AKT pathways in ES2 and OV90 cells. Chrysin inhibits tumor growth by cascading cancer cells through regulating the classical Wnt and nuclear factor NF-κB signaling pathways. Compared with the untreated control cells, Chrysin stimulated the phosphorylation of AKT and P70S6K proteins in ES2 and OV90 cells. In addition, Chrysin can also activate the phosphorylated ERK1/2, p38 and JNK proteins of MAPK pathway members in ovarian cancer cells.
Application&Function
Purpose
It is the raw material for synthesizing drugs with anti-cancer, lipid-lowering, cardiovascular and cerebrovascular disease prevention, antibacterial and anti-inflammatory effects.
Synthesize raw materials for anti-cancer, lipid-lowering, cardiovascular and cerebrovascular disease prevention, antibacterial, anti-inflammatory and other drugs.
Raw materials for synthesizing anti-cancer, lipid-lowering, cardiovascular and cerebrovascular disease prevention, antibacterial, anti-inflammatory and other drugs.
A flavonoid compound, similar to apigenin. It inhibits aromatase and also suppresses the activation of HIV in latent infection models. It has anti-inflammatory and antioxidant effects. Induce apoptosis of various cells, thereby demonstrating chemopreventive activity against cancer.
It is the raw material for synthesizing drugs that have anti-cancer, lipid-lowering, cardiovascular and cerebrovascular disease prevention, antibacterial and anti-inflammatory effects
Specification
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