Customization: | Available |
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Powder: | Yes |
Customized: | Negotiable |
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Product name | Artemether |
Cas number | 71963-77-4 |
density | 1.18 |
MF | C16H26O5 |
MW | 298.379 |
Cancer treatment
Artemisinin is undergoing early research and testing for the treatment of cancer.Chinese scientists have shown artemisinin has significant anticancer effects against human hepatoma cells.Artemisinin has a peroxide lactone group in its structure, and it is thought that when the peroxide comes into contact with high iron concentrations (common in cancerous cells), the molecule becomes unstable and releases reactive oxygen species. It has been shown to reduce angiogenesis and the expression of in some tissue cultures. Recent pharmacological evidence demonstrates the artemisinin-derivative dihydroartemisinin targets human metastatic melanoma cells with induction of NOXA (phorbol-12-myristate-13-acetate-induced protein 1)-dependent mitochondrial apoptosis that occurs downstream of iron-dependent generation of cytotoxic oxidative stress.