High Purity Pharmaceutical Milrinone Powder Milrinone
Product Description
| Product Name |
Milrinone |
| Appearance |
Milrinone Powder |
| Assay |
>99% |
| MW |
211.224 |
| MF |
C12H9N3O |
| Melting point |
>3000C |
| Boiling point |
448.7C |
Milrinone is a phosphodiesterase 3 (PDE3) inhibitor that works by increasing cardiac contractility and reducing pulmonary vascular resistance. It can also dilate blood vessels, reduce the pressure on the heart (afterload), and improve its pumping function. Although milrinone has been used for heart failure patients for many years, recent studies have shown that it may have some negative side effects, which has sparked controversy in clinical practice regarding its use. Overall, milrinone supports ventricular function by reducing the degradation of cAMP, thereby increasing the phosphorylation levels of many components in the heart that contribute to contractility and heart rate. However, the issue of using milrinone after heart surgery is still under debate, as there may be an increased risk of postoperative atrial arrhythmia. However, in the short term, milrinone is considered beneficial for people experiencing heart failure and is an effective treatment method that can maintain heart function after heart surgery. There is currently no evidence of any long-term benefits.
Application&Function
Milrinone is a phosphodiesterase 3 (PDE3) inhibitor primarily used for the treatment of heart failure.
Milrinone works by increasing the contractility of the heart and reducing pulmonary vascular resistance. It can also dilate blood vessels, reduce the pressure on the heart (afterload), and improve the pumping function of the heart. Although Milrinone has been used in human heart failure patients for many years, recent studies have shown that it may exhibit some negative side effects, which has sparked controversy in clinical practice regarding its use. Overall, Milrinone supports ventricular function by reducing the degradation of cAMP, thereby increasing the phosphorylation levels of many cardiac components involved in contractility and heart rate. However, there is some controversy surrounding the use of Milrinone after cardiac surgery, as it may increase the risk of postoperative atrial arrhythmias. However, in the short term, Milrinone is considered beneficial and an effective treatment for people experiencing heart failure and maintaining heart function after heart surgery. There is currently no evidence of any long-term beneficial effects on survival.
Specification
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