Antibiotic API Cyclosporin a CAS 59865-13-3 Cyclosporin a

• Customization: Available
• Powder: Yes
• Customized: Negotiable
• Model NO.: QS-Cyclosporin A
• Certification: GMP, HSE, ISO 9001, USP, BP
• State: Solid
• Purity: >99%
• Product Name: Cyclosporin a
• Name: Cyclosporin a Powder
• Appearance: White Powder
• Colour: White
• Grade: Pharmaceutical Grade
• Assay: >99%
• Application: API
• Specific: COA
• Test Method: HPLC
• Density: 1.016
• Mf: C62h111n11o12
• MW: 1202.635
• CAS: 59865-13-3
• Melting Point: 148-151c
• Boiling Point: 1293.8c
• Transport Package: Negotiable
• Specification: >99%
• Trademark: QS-Cyclosporin A
• Origin: Xian
• Production Capacity: 1000kg/Month

Product Description

Antibiotic API Cyclosporin A CAS 59865-13-3 Cyclosporin A

Product Description

Product Details

Product Name	Cyclosporin A
Appearance	Cyclosporin A Powder
Assay	>99%
MW	1202.635
MF	C62H111N11O12
Melting point	148-151C
Boiling point	1293.8C

Cyclosporin A is an immunosuppressant.
Cyclosporin A can bind to cyclophilin and has an IC50 value of 7nM for inhibiting calcineurin activity. Cyclosporin A also inhibits CD11a/CD18 adhesion molecules. Odorless and tasteless. Inhibiting T cell receptor signaling pathways for molecular biology research.

Application&Function

Cyclosporin A is a commonly used immunosuppressant that primarily reduces immune system activity by inhibiting T cell activity and growth.
Cyclosporin A inhibits the activity of protein phosphatase 2B (PP2B) by forming a complex with cyclophilin, ultimately suppressing the T cell receptor signaling pathway and achieving immunosuppressive effects. Cyclosporin A can also inhibit the synthesis of induced by interleukin-1 alpha, lipopolysaccharide (LPS), or TNF alpha; It can block cytochrome c release in mitochondria, but it can also induce apoptosis in rat lymphocytes and mouse B-cell lymphoma cell line WEHI-231.

Specification