Pharmaceutical CAS 1263-89-4 Paromomycin Sulfate API Paromomycin Sulfate
Product Description
Product Details
| Product Name |
Paromomycin Sulfate |
| Appearance |
Raw Paromomycin Sulfate Powder |
| Assay |
>99% |
| MW |
713.71 |
| MF |
C23H47N5O18S |
| Melting point |
>200 |
| Boiling point |
939.8C |
Paromycin Sulfate, as a broad-spectrum aminoglycoside antibiotic, has a wide range of antibacterial and antiparasitic effects, especially in the treatment of amoebic dysentery and other infections caused by sensitive bacteria, showing significant efficacy. However, its use also requires caution to avoid potential side effects and drug interactions.
Application&Function
Paromycin Sulfate is a broad-spectrum aminoglycoside antibiotic with multiple pharmacological effects, mainly including the following aspects:
1.Antibacterial activity
Baromycin sulfate has good antibacterial activity against both Gram negative and many Gram positive bacteria, as well as some protozoa and tapeworms. It exerts its antibacterial effect by binding to bacterial 16S ribosomal RNA, inhibiting protein synthesis.
2.Anti amoebic effect
Balonimycin sulfate can inhibit the symbiotic bacteria of amoebas, thereby hindering their growth and reproduction, indirectly exerting anti amoebic effects. It is a specific drug for treating amoebic dysentery and can also be used to treat bacterial dysentery and other gastrointestinal bacterial infections.
3.Antiparasitic effect
In addition to its effect on amoebas, paromycin sulfate also has good effects on parasites such as Leishmania parasites, Cryptosporidium, and filariasis.
4.Inhibit protein synthesis
Baromycin sulfate specifically binds to RNA oligonucleotides at the A site of the bacterial 30S ribosome, leading to premature termination of mRNA translation and inhibition of protein synthesis. This mechanism of action makes it an important tool for studying bacterial and parasitic infections.
Specification
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