| Customization: | Available |
|---|---|
| CAS No.: | 19171-19-8 |
| Formula: | C13h11n3o4 |
|
Still deciding? Get samples of $ !
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Product Name | Pomalidomide |
| Apperance | Yellow Powder |
| CAS | 19171-19-8 |
| MF | C13h11n3o4 |
| MW | 273.24 |
Purpose
Pomalidomide, chemically known as 4-amino-2 - (2, 6-dioxo-piperidin-3-yl) -isodihydroindole-1, 3-dione, is a thalidomide analogue and an immunomodulator with anti-tumor activity. In vitro cytological experiments, it can inhibit the proliferation of hematopoietic tumor cells and induce apoptosis. Furthermore, pomalidomide can inhibit the proliferation of lenalidomide-resistant multiple myeloma cell lines and synergistically induce tumor cell apoptosis in lenalidomide-sensitive and lenalidomide
Application
Pomalidomide has been used for:
BV173 cells were treated to investigate the role of the proteolytic targeted chimeric (PROTAC) compound JQ1-CRBN in inducing specific Class I major histocompatibility complex (MHC-I) peptides
For apoptosis research and intracellular calcium analysis
As a fetal hemoglobin (HbF) reagent for research on & #946; The cumulative effect of fetal hemoglobin expression levels in erythroid progenitor cells of thalassemia/variant hemoglobin E (HbE) and UNC0638
){kind=link}