Antiparkinsonism Pramipexole HCl Pharmaceutical Pramipexole
Product Description
Product Details
| Product Name |
Pramipexole |
| Apperance |
White Powde |
| CAS |
104632-26-0 |
| MF |
C10H17N3S |
| MW |
211.3 |
Pramipexole is a non ergot dopamine receptor agonist, chemical name (S) -2-amino-4,5,6,7-tetrahydro-6-propylamine benzothiazole dihydrochloride, CAS number 104632-26-0. The compound is a white or off white crystalline powder that is easily soluble in water. It mainly works by activating dopamine receptors in the brain and is clinically used to treat Parkinson's disease (PD) and restless leg syndrome (RLS). Due to its high selectivity and good tolerability, Pramipexole has become one of the important drugs for the treatment of neurodegenerative diseases.
Application&Function
The main function of Pramipexole is to act as a dopamine receptor agonist, directly stimulating dopamine receptors in the nigrostriatal pathway of the brain, thereby improving motor disorders such as tremors, rigidity, and bradykinesia in Parkinson's disease patients. In addition, it can regulate dopaminergic neurotransmission in the central nervous system, alleviating symptoms of restless leg syndrome such as nighttime leg discomfort and motor impulses. Compared to traditional ergot agonists, pramipexole has fewer side effects, is less likely to cause fibrotic reactions, and has a longer half-life, which can reduce medication frequency and improve patient compliance.
Specification
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