Pharmaceutical Intermediate Taxol API Anti-Tumour CAS 33069-62-4 Taxol Anti-Cancer Effect Taxol
Product Description

Product Details
Product Name |
Taxol |
Apperance |
White Powder |
CAS |
33069-62-4 |
MF |
C47H51NO14 |
MW |
853.918 g/mol |
Taxol is a natural anti-tumor drug that was originally extracted from the bark of Pacific yew (Taxus brevifolia) and is now mostly produced through semi synthetic or cell culture techniques. As a microtubule stabilizer, it can inhibit cancer cell division and is widely used in the treatment of breast cancer, ovarian cancer, lung cancer and other malignant tumors. Paclitaxel has become one of the core drugs in chemotherapy regimens due to its high efficacy and broad-spectrum anticancer activity. At present, multiple formulations of the drug have been developed, such as injectable albumin bound paclitaxel, to improve solubility and reduce side effects.
Application&Function
Paclitaxel promotes microtubule polymerization and inhibits its depolymerization by binding to microtubule proteins, leading to the arrest of cancer cell mitosis in the G2/M phase and inducing apoptosis. Its unique mechanism of action makes it highly selective towards rapidly proliferating tumor cells. In addition, paclitaxel can inhibit tumor angiogenesis and enhance immune response. Although the therapeutic effect is significant, common side effects include bone marrow suppression, neurotoxicity, and allergic reactions. Clinical use requires the use of pre-treatment regimens (such as antihistamines and hormones) to reduce risk.
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