Constipation Picosulfate Sodium Powder picosulfate Sodium
Product Description
Product Details
| Product Name |
Picosulfate Sodium |
| Appearance |
White Powder |
| Assay |
99% |
| MW |
481.41 |
| MF |
C18H13NO8S2.2Na |
Pharmacological effects of sodium picosulfate:
Picklesulfate sodium is a special laxative with a unique mode of action, which is metabolized into diphenolic metabolites through the intestinal microbiota. This compound can cause excessive intestinal peristalsis, stimulate the intestinal mucosa, and reduce water absorption, thereby producing a laxative effect. The laxative effect of sodium picosulfate is mild and suitable for various constipation conditions, postoperative assisted defecation, promotion of defecation after contrast agent administration, preoperative removal of intestinal contents, pre-treatment of colon examination (endoscopy), and removal of intestinal contents.
Application&Function
Picklesulfate sodium is a special laxative with a unique mode of action, which directly acts on the colon mucosa to produce a mild laxative effect.
Sodium picosulfate has good clinical efficacy, minimal side effects, and a high safety factor. Studies have shown that sodium picosulfate does not cause gastrointestinal reactions and is hydrolyzed by the hydrolytic enzymes of the colonic microbiota to produce diphenols, which exert a laxative effect. Among them, sodium picosulfate exhibits good moisturizing and laxative effects. The site of action of sodium picosulfate is the colon, which is hydrolyzed by enzymes produced by the colonic microbiota to produce active components such as catechins. It can directly stimulate the intestinal mucosa, promote intestinal peristalsis, and inhibit the absorption of water in the intestine, demonstrating its laxative effect. The excretion in urine shows that sodium picosulfate has almost no absorption in the gastrointestinal tract and has little systemic effect. Its efficacy is independent of the plasma concentration of the active ingredient. Picklesulfate sodium is a commonly used laxative in clinical practice abroad, with markets in multiple countries including Italy, Germany, Japan, Australia, and others. Sodium Picosulfate is a special laxative with a unique mode of action, which is metabolized by the intestinal microbiota into diphenolic metabolites. This compound can cause intestinal peristalsis, stimulate the intestinal mucosa, reduce water absorption, and thus produce a laxative effect. The laxative effect is mild and suitable for various constipation, postoperative assisted defecation, promotion of defecation after contrast agent administration, preoperative removal of intestinal contents, pre-treatment of colon examination (endoscopy), and removal of intestinal contents.
Specification
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